This chapter discusses the issue of designing projects and actions to manage complex problems, often amongst people with very different cultures and backgrounds. Challenges arise in engaging local people when designing interventions as well as in setting up goals and outcomes as well as coordinating work between different types of practitioners. The Theory of Change is a framework that allows to see the existing preconditions and the cross-disciplinary-thinking they require, and the short-, medium-, and long-term outcomes that comprise the basis for action. It’s important to bridge the gap between your own cultural upbringing and that of the society with whom you are working. Long-term change comes from early childhood development. Know the stakeholders in your strategies and create participatory solutions.