In this chapter, Massari discusses how universities, educational institutions, and professors need to adjust their focuses and take responsibility for institutional innovation. Academic structures have to be reframed to encourage innovation, and advanced education for sustainable development, specifically secondary and vocational education. The educational system will need to prepare individuals for the changing labor market and to be life-long learners, and make use of ICT to give wider access to education. We need to facilitate cooperation and collaboration because humans are social creatures. We have to create bridges between academia and those who work in the field. People need to learn how to learn, instead of just to learn contents, and must be self-motivated to keep learning. There are three case studies: food studies programs in higher education in the United States, the transdisciplinary design workshop of project-based learning, and co-op based learning that brings the real world inside of the classroom. This chapter is part of Module 10: New Professional Profiles in a Mediterranean Context.