This chapter profiles a number of initiatives focused on innovation for energy and they connect to investment and policy. One is Mission Innovation, which includes 20 countries committed to investing about US$15 billion dollars a year in energy technology R&D and double that to US$30 billion dollars over a five-year period. They represent approximately 75 to 80 percent of the world's investment in clean energy technology. Another is Breakthrough Energy Coalition, which is putting forward capital to take advantage of the expanded innovation pipeline. The emphasis made by former U.S. Secretary of Energy Ernest Moniz is innovation that links governments, investors, entrepreneurs, and technologists. He also stresses other concerns such as jobs. Finally, he notes that different regions will have different makeups for their innovation systems, as local context is necessary to understand and drive innovation.